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Melatonin improves sleep during hypertension treatment

Filed in
  • Melatonin
  • Hypertension

American Academy of Sleep Medicine  |  Oct 01, 2012
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Melatonin supplements may improve sleep in hypertension patients who are on beta-blockers. Scientists found that three weeks of melatonin use significantly improved their sleep quality and helped them stay asleep compared with a placebo.

Patients taking melatonin increased total sleep time by 37 minutes. They also spent less time awake in bed, and fell asleep quicker. The authors of the study, published in the journal SLEEP observed that the melatonin improved sleep tolerence without the common side effects of drug tolerance or rebound insomnia.

Beta-blockers are drugs that affect the body’s response to certain nerve impulses and are sometimes used in hypertension patients. These medications suppress endogenous nighttime melatonin secretion, which may explain a reported side effect of insomnia.

Melatonin is effective in resetting the body's circadian rhythms, and is used frequently for jet lag. Findings are mixed on whether melatonin helps improve sleep in otherwise healthy patients with insomnia.

If you have insomnia and are not on a beta-blocker, there are other ways you can tackle your insomnia. These include cognitive behavioral therapy and medications. The AASM advises you to talk to your doctor before taking melatonin or any medication. Your doctor may refer you a sleep medicine physician at an AASM-accredited sleep disorders center. Click here to find an AASM-accredited sleep center near you.


  1. 1 John 23 Mar
    I have yet to meet a physician that is aware of the connection between beta-blockers and insomnia.
  2. 2 Fatima 10 Nov
    Your not alone friend. I have both as you do and what I sugsget is now that you have the machine, you go to your doctor and get a sleep aid that can be accompanied by an antihistamene. Let me tell you I am on Trazadone for sleep and hydroxyzine which is the antihistamene. Together they work wondurfully. Also you may be overweight which many are who have apnea. Try not to drink too much water and if you are getting up in the night to urinate often then ask your doctor for a diuretic which will reduce the overall body fluid in the body. You may want to look into the possibility of type 2 diabetes. Hope this helps. Hang in there it gets better.p.s. I am awake by choice as i was off yesterday catnapping all day in the rainy weather. Just so you don't ask yourself, Why is he not asleep then? LOL